Differences between platinum and diamond supports?

2022.01.18 07:45 aprl2104 Differences between platinum and diamond supports?

Hi! I started climbing for the first time last season from silver 1 to plat 3 as support and looking to hit diamond in 2022. Can any high elo players who've played in these ranks point out any differences between platinum and diamond supports? I play engage supports only like Nautilus, Leona, and Alistar. Any tips would be appreciated 🙂👍
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2022.01.18 07:45 FancyPea677 British aircraft joins operation to track ‘on the move’ Russian fleet.

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2022.01.18 07:45 w0lfcat XSS in 500 Internal Server Error HTTP Response?

When a site return 500 Internal Server Error with the whole headers in it including User-Agent
HTTP Response

HEADERS ======= ... User-Agent: Mozilla  ... 
Does this consider as a valid XSS finding? Burp Suite Pro says this is certain, however I did not get any popup though with this payload on web browser. All I get is bunch of error message with complete HTTP HEADERS at the bottow of the browser.
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2022.01.18 07:45 niuz-bot Stelian Ion: Cătălin Predoiu, pe lista scurtă de miniştri care riscă o moţiune simplă - [Politica]

Vicepreşedintele USR Stelian Ion îi cere ministrului Justiţiei, Cătălin Predoiu, să renunţe la "fantasmagoria" de a propune un nou proiect de desfiinţare a Secţiei pentru Investigarea Infracţiunilor din Justiţie, menţionând că USR ar putea depune o moţiune simplă împotriva ace...
Citeste in continuare: https://www.agerpres.ro/politica/2022/01/18/stelian-ion-catalin-predoiu-pe-lista-scurta-de-ministri-care-risca-o-motiune-simpla--849155
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2022.01.18 07:45 Easy-Information4287 Cloudwatch Metrics - How to trigger an alarm when the number of requests is 20% lower today than yesterday ?

I would like to have a metric that compare today's vs yesterday's sum.
For example yesterday the sum value was 100 for 1 day, today it's 80. I would like the metric to be something that compute (100-80)/100 so if it's higher than 0.2 I know there were a gap in the number of requests and I can trigger an alarm.
I know there is a standard deviation feature in the alarm aws console but it's hard to setup precisely.
Thanks
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2022.01.18 07:45 cocoaredicecream Nike First Responder Discount

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2022.01.18 07:45 yasharghasemi1384 New Members Intro

If you’re new to the community, introduce yourself!
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2022.01.18 07:45 ComradeCommissary Bringing into play the Military’s politico-spiritual factor in non-traditional security challenge prevention and control

Bringing into play the Military’s politico-spiritual factor in non-traditional security challenge prevention and control submitted by ComradeCommissary to GenHoChiMinh [link] [comments]


2022.01.18 07:45 AutoModerator Meu projeto de closet

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2022.01.18 07:45 citylightspulsar Lowe's 20% Discount Code

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2022.01.18 07:45 spwn_srujan A great place for a 2D open world game to take place?

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2022.01.18 07:45 Acidcatfish99 We need the Super Smash Bros Ultimate arrangement of Halland in vanilla as a music disk and I'm serious.

We need the Super Smash Bros Ultimate arrangement of Halland in vanilla as a music disk and I'm serious. submitted by Acidcatfish99 to Minecraft [link] [comments]


2022.01.18 07:45 dischead20 me_irl

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2022.01.18 07:45 Tombstone_Actual_501 To do math.

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2022.01.18 07:45 caramel1090 Check

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2022.01.18 07:45 niuz-bot APC solicită transparenţă din partea ANPC cu privire la acţiunile de control specifice Comandamentului pentru Energie - [Economic]

Asociaţia Pro Consumatori (APC) solicită transparenţă din partea Autorităţii Naţionale pentru Protecţia Consumatorilor (ANPC) cu privire la acţiunile de control specifice Comandamentului pentru Energie, se precizează într-o scrisoare deschisă transmisă marţi AGERPRES.
"Asoc...
Citeste in continuare: https://www.agerpres.ro/economic-intern/2022/01/18/apc-solicita-transparenta-din-partea-anpc-cu-privire-la-actiunile-de-control-specifice-comandamentului-pentru-energie--849148
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2022.01.18 07:45 External_Clue_8635 if anyone wants the template just let me know

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2022.01.18 07:45 shivamconan101 How true are the fear of false rape cases would destroy lives of more males after martial rape law?

To start off, I absolutely support martial rape law to come. There have been few arguments against it though from conservatives and MRA. One is that it will destroy marriage as an institution and societal structure. This is a ridiculous argument. If sex is being done forcefully, the "institution" of marriage has already fell apart. Other is false cases.
As a male I am not able to wrap around my head for false cases. I see plenty of reports on them & the fears seems to be coming from a valid place due to our legal system loopholes.
Rape in India

In 2014, as per a report submitted by Delhi Commission for women 53% of reported rapes in 2012-13 were found to be 'false'. This report considered the cases that were dropped before going to trial as false, and failed to differentiate between the cases dropped due to coercion and cases where it was clear that women were lying.
I have zero knowledge on legality but it seems that women testimony alone is sufficient in case of rape based on my reading. This can be tricky in case of martial rape because our laws are not gender neutral yet (male is always perpetrator) and it can be difficult for man to prove that consent was indeed there if the wife denies it later in court.
This is not an argument against the presence of martial rape laws but more of argument against absence of legal measures to address this problem. India has higher %age of fake cases than western countries which is a unique situation. Your thoughts?
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2022.01.18 07:45 Gseahorse Wormate.io Epic Trolling On Server In Wormateio Epic Gameplay

Wormate.io Epic Trolling On Server In Wormateio Epic Gameplay submitted by Gseahorse to PromoteGamingVideos [link] [comments]


2022.01.18 07:45 Genetic_Problemz Anyone else hate their job?

Constantly clock watching is killing me, any advice on how to make a shit job not suck ass as much? I wanna quit but only staying for the salary, I was wondering if anyone else felt this way.
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2022.01.18 07:45 Sorin61 Erinacine A Prevents Lipopolysaccharide-Mediated Glial Cell Activation to Protect Dopaminergic Neurons against Inflammatory Factor-Induced Cell Death In Vitro and In Vivo , study [ 01 - 2022 ]

Hericium erinaceus (HE) is a common edible mushroom consumed in several Asian countries and considered to be a medicinal mushroom with neuroprotective effects.
Erinacine A (EA) is a bioactive compound in Hericium erinaceus mycelium (HEM) that has been shown to have a neuroprotective effect against neurodegenerative diseases, e.g., Parkinson’s disease (PD). Although the etiology of PD is still unclear, neuroinflammation may play an important role in causing dopaminergic neuron loss, which is a pathological hallmark of PD. However, glial cell activation has a close relationship with neuroinflammation.
Thus, this study aimed to investigate the anti-neuroinflammatory and neuroprotective effects of EA on lipopolysaccharide (LPS)-induced glial cell activation and neural damage in vitro and in vivo. For the in vitro experiments, glial cells, BV-2 microglial cells and CTX TNA2 astrocytes were pretreated with EA and then stimulated with LPS and/or IFN-γ.
The expression of proinflammatory factors in the cells and culture medium was analyzed. In addition, differentiated neuro-2a (N2a) cells were pretreated with EA or HEM and then stimulated with LPS-treated BV-2 conditioned medium (CM).
The cell viability and the amount of tyrosine hydroxylase (TH) and mitogen-activated protein kinases (MAPKs) were analyzed. In vivo, rats were given EA or HEM by oral gavage prior to injection of LPS into the substantia nigra (SN). Motor coordination of the rats and the expression of proinflammatory mediators in the midbrain were analyzed. EA pretreatment prevented LPS-induced iNOS expression and NO production in BV-2 cells and TNF-α expression in CTX TNA2 cells.
In addition, both EA and HEM pretreatment significantly increased cell viability and TH expression and suppressed the phosphorylation of JNK and NF- κB in differentiated N2a cells treated with CM. In vivo, both EA and HEM significantly improved motor dysfunction in the rotarod test and the amphetamine-induced rotation test and reduced the expression of TNF-α, IL-1β and iNOS in the midbrain of rats intranigrally injected with LPS.
The results demonstrate that EA ameliorates LPS-induced neuroinflammation and has neuroprotective properties.

Full text :
- https://www.mdpi.com/1422-0067/23/2/810/htm
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2022.01.18 07:45 ichooseju I'll draw stuff for you! ( quick, probably colored, sketches)

Gimme some stuff from OC's, to Characters to Pokémon and i'll see what I can do!
You can look at previous art from me here!
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2022.01.18 07:45 barnyard9 What was you favorite computer science/engineering subject?

For me in this order
1) Distributed system-: I almost failed this because I suffered from burnout before exams but I learnt this subject first time totally on my own by reading bigass books. I am proud of that lol. Pride in defeat. haha
2) Theory of computation-: Fabulous subject. I have failed twice and might fail thrice in this subject lol but I loved studying this subject. Reason here is burnout due to overstudying as well. I am suffering from some serious mental health issues and that doesn't help as well.
Also what are you planning to do master's on? I am thinking about doing masters in electronics or electrical engineering sciences.
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2022.01.18 07:45 LectureSea7537 Thanks i hate refular cooking

Thanks i hate refular cooking submitted by LectureSea7537 to thanksihateit [link] [comments]


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